NCP - Omega-3 FA Mechanisms And Abrogation Of Tumor-Related Syndromes

Babcock TA, Dekoj T, Espat NJ.

Source

Department of Surgery, University of Illinois at Chicago, Chicago, IL 60612, USA.

Abstract

Clinical and experimental evidence has supported a benefit for the inclusion of fish oils (a primary source of omega-3 fatty acids) as a component of a normal healthy diet. Polyunsaturated omega-3 fatty acids have been demonstrated to be of benefit in a number of inflammation-associated disease states, including atherosclerosis, autoimmune disorders, malignancy, and sepsis. The beneficial effects of omega-3 fatty acids are thought to occur through the postulated antiinflammatory actions of omega-3 fats; however, the specific mechanism(s) of action has not been completely defined. In this review, we discuss the recent progress made in our laboratory on defining the mechanisms of omega-3 fatty acids activity.

PMID:

 

16207647

 

[PubMed - indexed for MEDLINE]