BrJC – High Omega-6 and Colon Cancer Risk

Koh WP, Yuan JM, van den Berg D, Lee HP, Yu MC.

Source

Department of Community, Occupational and Family Medicine, National University of Singapore, MD3, 16 Medical Drive, Singapore 117597, Singapore. cofkwp@nus.edu.sg

Abstract

This case-control study of 310 colorectal cancer cases and 1177 controls in a nested prospective, population-based cohort of Singapore Chinese subjects found a statistically significant association between the cyclooxygenase (COX)-2 -765G>C gene polymorphism and colon cancer risk among high consumers of dietary n-6 polyunsaturated fatty acids (odds ratio=2.38, 95% confidence interval=1.23-4.59).

PMID:

 

15150618

 

[PubMed - indexed for MEDLINE]